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CIE · IGCSE · Biology

Variation and Selection
Practice Questions

86 CIE IGCSE Biology questions on Variation and Selection, each with instant feedback and a full examiner-style mark scheme.

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✨ Revision guide includes key terms, worked examples and exam technique for Variation and Selection.

Try 2 sample questions on Variation and Selection

Question 1 · 1 mark · Difficulty 1/3

A gene mutation occurs in which part of a cell?

  1. The nucleus, in the DNA
  2. The cytoplasm, in the mRNA
  3. The cell membrane, during cell division
  4. The ribosomes, during translation
Show answer & explanation
✓ Answer: A — The nucleus, in the DNA
Gene mutations are changes to the base sequence of DNA, which is located in the nucleus of the cell. Ribosomes and cytoplasm are sites of protein synthesis, not of the genetic material itself.
Question 2 · 1 mark · Difficulty 1/3

How many genetically unique daughter cells are produced at the end of meiosis?

  1. Four haploid cells
  2. Four diploid cells
  3. Two diploid cells
  4. Two haploid cells
Show answer & explanation
✓ Answer: A — Four haploid cells
Meiosis produces four haploid daughter cells, each genetically unique due to independent assortment and crossing over. Two diploid cells describes mitosis's output (or the first division only). Two haploid cells is incorrect because meiosis II splits both secondary oocytes/spermatocytes. Four diploid cells would incorrectly restore the full chromosome number.
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20 questions · 25 min · free

CIE IGCSE Biology: Variation and Selection FAQ

Is Kramizo free for CIE IGCSE students preparing for Biology?
Yes — completely free. Every student gets 45 questions a day on the free plan, with no card required and no trial countdown. That free quota works across every subject and every topic in our bank, so you can mix Variation and Selection practice with other Biology topics or even switch to a totally different CIE subject without paying anything. Kramizo's optional Pro plan removes the daily cap and adds detailed progress analytics, but the free tier is the real product — used by thousands of GCSE, IGCSE and CSEC students.
Are the Variation and Selection questions aligned to the official CIE IGCSE Biology syllabus?
Every question is written against the published CIE IGCSE Biology specification, including the exact command words (state, describe, explain, calculate, evaluate, etc.), mark allocations, and difficulty tier you'd see on a real CIE paper. Explanations are written in the style of official examiner mark schemes — they tell you what is being awarded marks and why distractors are wrong, not just whether you got it right. The bank is continually refined to match the latest syllabus updates from CIE.
How is Variation and Selection typically tested on CIE IGCSE Biology papers?
Variation and Selection appears across multiple question types on real CIE IGCSE Biology papers — most commonly as multiple-choice questions in the objective section, structured short-answer questions in the main paper, and occasionally as part of an extended response. Kramizo's practice bank reflects that mix: 4-option MCQs, true/false statements, fill-in-the-blank key terms, multi-select questions, and ordering questions. Working through the bank gives you exposure to every question style examiners actually use.

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