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HomeCXC CSEC Human and Social BiologyGenetic diseases: sickle cell anaemia, haemophilia and Down syndrome
CXC · CSEC · Human and Social Biology

Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome
Practice Questions

20 CXC CSEC Human and Social Biology questions on Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome, each with instant feedback and a full examiner-style mark scheme.

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Question 1 · 1 mark · Difficulty 1/3

A clinic in Kingston, Jamaica screens newborns for genetic disorders. One baby is found to have abnormally shaped red blood cells that appear crescent-shaped under the microscope. Which genetic disease does this baby most likely have?

  1. Haemophilia
  2. Sickle cell anaemia
  3. Down syndrome
  4. Diabetes mellitus
Show answer & explanation
✓ Answer: BSickle cell anaemia
Award 1 mark for identifying sickle cell anaemia as the condition characterised by crescent-shaped (sickle-shaped) red blood cells. A is incorrect — haemophilia affects blood clotting, not red blood cell shape. C is incorrect — Down syndrome is a chromosomal disorder affecting chromosome 21, not red blood cell shape. D is incorrect — diabetes mellitus is a metabolic disorder, not a genetic blood disorder.
Question 2 · 1 mark · Difficulty 1/3

Which of the following correctly describes the inheritance pattern of haemophilia?

  1. Autosomal dominant
  2. Autosomal recessive
  3. Sex-linked recessive
  4. Sex-linked dominant
Show answer & explanation
✓ Answer: CSex-linked recessive
Award 1 mark for identifying haemophilia as a sex-linked recessive condition carried on the X chromosome. A and B are incorrect — haemophilia is not autosomal as the gene is located on the X chromosome. D is incorrect — haemophilia is recessive, not dominant, which is why female carriers typically do not show symptoms.
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CXC CSEC Human and Social Biology: Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome FAQ

How many CXC CSEC Human and Social Biology questions on Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome are there on Kramizo?
Kramizo currently has 20 exam-board-aligned practice questions on Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome for CXC CSEC Human and Social Biology, with new questions added every week. Each question gives you instant feedback and a full examiner-style mark scheme that tells you exactly what would earn marks on a real CXC paper. The questions span the full difficulty range — from straightforward recall (level 1) right up to multi-step reasoning and evaluation (level 3) — so the bank works for first-pass revision and final exam-week stress testing alike.
Is Kramizo free for CXC CSEC students preparing for Human and Social Biology?
Yes — completely free. Every student gets 45 questions a day on the free plan, with no card required and no trial countdown. That free quota works across every subject and every topic in our bank, so you can mix Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome practice with other Human and Social Biology topics or even switch to a totally different CXC subject without paying anything. Kramizo's optional Pro plan removes the daily cap and adds detailed progress analytics, but the free tier is the real product — used by thousands of GCSE, IGCSE and CSEC students.
Are the Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome questions aligned to the official CXC CSEC Human and Social Biology syllabus?
Every question is written against the published CXC CSEC Human and Social Biology specification, including the exact command words (state, describe, explain, calculate, evaluate, etc.), mark allocations, and difficulty tier you'd see on a real CXC paper. Explanations are written in the style of official examiner mark schemes — they tell you what is being awarded marks and why distractors are wrong, not just whether you got it right. The bank is continually refined to match the latest syllabus updates from CXC.
How is Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome typically tested on CXC CSEC Human and Social Biology papers?
Genetic diseases: sickle cell anaemia, haemophilia and Down syndrome appears across multiple question types on real CXC CSEC Human and Social Biology papers — most commonly as multiple-choice questions in the objective section, structured short-answer questions in the main paper, and occasionally as part of an extended response. Kramizo's practice bank reflects that mix: 4-option MCQs, true/false statements, fill-in-the-blank key terms, multi-select questions, and ordering questions. Working through the bank gives you exposure to every question style examiners actually use.

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