A pregnancy test uses monoclonal antibodies to detect the hormone hCG. If the antibodies on the test strip are NOT complementary to hCG, which result would occur?

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Question

A pregnancy test uses monoclonal antibodies to detect the hormone hCG. If the antibodies on the test strip are NOT complementary to hCG, which result would occur?

Accepted Answer

C. The test would not produce a positive result even if hCG is present — Monoclonal antibodies only bind to the specific antigen that is complementary to their binding site. If the antibodies are not complementary to hCG, they cannot bind to it, so no positive result would be produced even if hCG is present. This illustrates the high specificity that makes monoclonal antibodies so useful in diagnostic tests.

Answer

A. The test would show a false positive result

Answer

B. The test would show a positive result only if hCG is very concentrated

Answer

D. The test would react with all hormones present in urine

Answer

C. The test would not produce a positive result even if hCG is present

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