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Mutation
Practice Questions

20 CIE IGCSE Biology questions on Mutation, each with instant feedback and a full examiner-style mark scheme.

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Try 2 sample questions on Mutation

Question 1 · 1 mark · Difficulty 1/3

Which of the following is the correct definition of a mutation?

  1. A change in the base sequence of DNA
  2. A change in the number of chromosomes only
  3. An error that occurs only during meiosis
  4. A change caused exclusively by radiation
Show answer & explanation
✓ Answer: A — A change in the base sequence of DNA
A mutation is defined as a change in the base sequence of DNA. This can involve a substitution, insertion, or deletion of one or more bases. Mutations can occur spontaneously or be induced by mutagens.
Question 2 · 1 mark · Difficulty 1/3

A gene mutation occurs in which part of a cell?

  1. The ribosomes, during translation
  2. The nucleus, in the DNA
  3. The cytoplasm, in the mRNA
  4. The cell membrane, during cell division
Show answer & explanation
✓ Answer: B — The nucleus, in the DNA
Gene mutations are changes to the base sequence of DNA, which is located in the nucleus of the cell. Ribosomes and cytoplasm are sites of protein synthesis, not of the genetic material itself.
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20 questions · 25 min · free

CIE IGCSE Biology: Mutation FAQ

How many CIE IGCSE Biology questions on Mutation are there on Kramizo?
Kramizo currently has 20 exam-board-aligned practice questions on Mutation for CIE IGCSE Biology, with new questions added every week. Each question gives you instant feedback and a full examiner-style mark scheme that tells you exactly what would earn marks on a real CIE paper. The questions span the full difficulty range — from straightforward recall (level 1) right up to multi-step reasoning and evaluation (level 3) — so the bank works for first-pass revision and final exam-week stress testing alike.
Is Kramizo free for CIE IGCSE students preparing for Biology?
Yes — completely free. Every student gets 45 questions a day on the free plan, with no card required and no trial countdown. That free quota works across every subject and every topic in our bank, so you can mix Mutation practice with other Biology topics or even switch to a totally different CIE subject without paying anything. Kramizo's optional Pro plan removes the daily cap and adds detailed progress analytics, but the free tier is the real product — used by thousands of GCSE, IGCSE and CSEC students.
Are the Mutation questions aligned to the official CIE IGCSE Biology syllabus?
Every question is written against the published CIE IGCSE Biology specification, including the exact command words (state, describe, explain, calculate, evaluate, etc.), mark allocations, and difficulty tier you'd see on a real CIE paper. Explanations are written in the style of official examiner mark schemes — they tell you what is being awarded marks and why distractors are wrong, not just whether you got it right. The bank is continually refined to match the latest syllabus updates from CIE.
How is Mutation typically tested on CIE IGCSE Biology papers?
Mutation appears across multiple question types on real CIE IGCSE Biology papers — most commonly as multiple-choice questions in the objective section, structured short-answer questions in the main paper, and occasionally as part of an extended response. Kramizo's practice bank reflects that mix: 4-option MCQs, true/false statements, fill-in-the-blank key terms, multi-select questions, and ordering questions. Working through the bank gives you exposure to every question style examiners actually use.

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